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Siemens Medical Solutions


Role: Principal Investigator

Direct Costs: $150,000/yr.

July 1, 2001 – June 30, 2006

EISAI Medical Research Phase I and Pharmacokinetic StudyE7820 (LIFE) after Oral Administration to Patients with Malignancy


Role: Principal Investigator

June 29, 2004 – August 31, 2005

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NIH R01 High Resolution BOLD Venographic Imaging


Role: Principal Investigator

Direct costs $750,000

June 16, 2001 – May 31, 2004


  1. NIH grant "Quantitative Measurement of Brain Oximetry using MRI"

Role: Consultant Time 10%

Budget: $200,000 for three years from December 1, 1999 - November 30, 2002

Principal Investigator: Weili Lin at University of North Carolina in Chapel Hill


  1. NIH grant “Coronary Artery Imaging” from 2000 to 2003

Role: Consultant

Principal Investigator: Debiao Li at Northwestern University in Chicago


  1. Janssen Research Foundation “3D Imaging of the Brain”

Role: Principal Investigator

Budget: $93,200 October 1999 - October 2000


  1. NIH R01, “MRI of Coronary Artery Disease”

Role: Principal Investigator: Time 30%

Budget: $750,000 for three years from 1997 - 1999


  1. NIH R01, “Tissue Water Measurements of Brain Edema with MRI”

Role: Co-investigator: Time 10%

Budget: $597,889 for four years from 1 April, 1996 - 31 March, 2000


  1. NINDS program project grant with Marcus Raichle (co-investigator)

on the fMRI CORE section.

Role: Investigator: Time 15% of Project 1

Budget: $673,386 for five years from Dec., 1994 - Nov. 30, 1999


  1. RSNA “Identification of Proximal Coronary Artery Stenoses with 3D MR Retrospective Respiratory Gating”

Role: Advisor. Principal Investigator: Pamela Woodard

Budget: $70,000 for two years from July, 1996 - June, 1998


  1. NIH R01 "MRI of the central cardiovascular system"

Role: Principal Investigator: Time 30%.

Budget: $1,108,384 for five years from 1 Aug., 1990 - 31 July, 1995



  1. Shared Instrumentation Grant with Joe Ackerman

Role: Co-investigator

Budget: $400,000 in 1995


  1. NIH R01 "MR flow techniques for cerebrovascular disease"

Role: Consultant: Time 10%.

Budget: $694,478 for three years from 1 Aug., 1990 - 31 July, 1993


  1. NASA Grant, “Phase Shifting Interferometry to Measure Object Displacement V"

Role: Principal Investigator: Time 10%

Budget: $47,355 for one year from 5 Dec. 1991 - 4 Dec. 1992


  1. NASA Grant, "Phase Shifting Interferometry to Measure Object Displacement IV"

Role: Principal Investigator: Time 10%

Budget: $47,355 for one year from 5 Dec. 1990 - 4 Dec. 1991


  1. NASA Grant, "Phase Shifting Interferometry to Measure Object Displacement III"

Role: Principal Investigator: Time 10%

Budget: $45,940 for one year from 5 Dec., 1989 - 4 Dec 1990


  1. NASA Grant, "Phase Shifting Interferometry to Measure Object Displacement II"

Role: Principal Investigator: Time 10%

Budget: $40,221 for one year from 5 Dec. 1988 to 4 Dec. 1989


  1. NASA Grant, "Phase Shifting Interferometry to Measure Object Displacement I"

Role: Principal Investigator: Time 5%

Budget: $21,922 for one year from 5 Dec. 1987 to 4 Dec. 1988


  1. Whitaker Foundation, “RF penetration in MRI”

Role: Principal Investigator: Time, 10%

Budget $180,000 for three years from Oct. 30, 1988 - Oct. 29, 1991


  1. American Heart Association Grant, "Oxygen-17 as a contrast agent in cerebral ischemia and stroke"

Role: Co-investigator: Time 10%.

Budget: $18,043.75 for one year from Jan., 1989 to 31 Dec. 1989


  1. American Heart Association Grant, "Oxygen-17 water as an MRI myocardial contrast agent”

Role: Co-investigator 5%.

Budget: $10,750 for one year from 1 Jan., 1987 to 31 Dec. 1987


  1. CWRU research initiation grant $5,000.

Role: Principal Investigator.

Budget: $5,000 for one year from 1 Jan., 1987 to 30 Nov. 1987


14. Industrial Grants:


  1. Siemens Medical Solutions “Susceptibility Weighted Imaging”

Role: Principal Investigator

Budget: $100,000 for 3 years (2006-2009)


  1. Siemens AG “Susceptibility Weighted Imaging”

Role: Principal Investigator

Budget: $150,000 for 5 years (2001-2005)


  1. Siemens Medical Systems, "Partial Fourier Imaging"

Role: Co-Principal Investigator

Budget: $50,000 for the year 2001



  1. Siemens Medical Systems, "AVID BOLD Imaging"

Role: Principal Investigator

Budget: $50,000 for the year 2001


  1. Arbor Consulting Resources, “Vessel Segmentation”

Role: Principal Investigator

Budget: $150,000 for one year from Oct., 1996 - Sept., 1997


  1. Siemens Medical Systems, "fMRI and Cardiovascular MRI Research"

Role: Principal Investigator

Budget: $600,000 for four years from 1 July, 1994 - 30 June, 1999


  1. EPIX/MMI, “Separating Arteries and Veins in Contrast Enhanced MRI”

Role: Principal Investigator

Budget: $225,000 for one year from May, 1997 - October, 1999



  1. Mallinckrodt Medical Inc./Mallinckrodt Institute of Radiology Research Program

Role: Co-Investigator. Time 5%

Budget: $65,000 for one year from 1 July 1995 - June 30, 1996


  1. Metasyn, “MR of Coronary Arteries with MS - 325”

Role: Co-investigator

Budget: $45,000 for one year, 1996


  1. Metasyn, “MR of Coronary Arteries with MS - 325”

Role: Co-investigator

Budget: $45,000 for one year, 1995


  1. Edison Biotechnology Center Grant, “Superresolution Imaging”

Role: Principal Investigator

Budget: $76,000 for one year from 1 Sept, 1990 - 31 Aug., 1991


  1. Edison Biotechnology Center Grant, “Superresolution Imaging”

Role: Principal Investigator

Budget: $45,000 for one year from 1 Oct. 1989 - 30 Sept., 1990


  1. Pfizer Research Grant, “The use of Magnetic Resonance Imaging to evaluate the efficacy of anti-inflammatory and analgesic therapy on osteoarthritic articular cartilage”

Role: Co-investigator

Budget: $60,000 for one year from 1989-1990


  1. Edison Biotechnology Center Grant, “In Vivo Biomicroscopy with Ultrasound”

Role: Co-investigator

Budget: $38,000 for one year from 1988-1989


  1. Discretionary Imaging Grant. Over $100,000 in support for students from several sources have been channeled through two discretionary accounts at CWRU during 1985 through 1988




  1. Technicare for student support, “MRI reconstruction techniques”

Role: Principal Investigator.

Budget: $5,000 for one year, 1986


15. Grants participated in as Advisor, Consultant, Mentor, or Investigator:


  1. GE-AUR Award

PI: Karen A. Tong, M.D., Loma Linda University, CA. Imaging Traumatic Brain Imaging with MuF (short title) 2001



  1. NIH - R01

Quantitative Brain Oximetry Using MRI”

December 1 1998 - November 3, 2003, Total budget: $1,793,109

Principal Investigator: Weili Lin, 35% effort

Consultant: Mark Haacke


  1. NIH - R01

Tissue Water Measurement of Brain Edema with MRI”

April 1, 1996 - March 3, 2000, Total budget: $791,233

Principal Investigator: Weili Lin 25% effort

Consultant: Mark Haacke


  1. NIH - R01

MRI of Coronary Artery Disease”

December 1, 1996 - November 30, 1999, Total budget: $749,546

Principal Investigator: Debiao Li

PI of Subcontract: Mark Haacke, 25% effort


  1. RSNA

Identification of Proximal Coronary Artery Stenoses with 3D MR Retrospective Respiratory Gating”

July 1996 - June 1998, Total budget: $70,000

Role: Advisor

Principal Investigator: Pamela Woodard


  1. NIH, 5 P01 NS06783

The Brain and Its Vasculature”

December 1994 - November 1999, Total budget: $670,000

Role: Co-Investigator - Mark Haacke 15%,

Principal Investigator: Marcus E. Raichle



  1. NIH 7 R01 NS24724

Efficacy of MRI Angiography in Cerebrovascular Diseases"

September 1993 - August 1994, Total budget: $100,000

Role: Co-Investigator: Mark Haacke

Principal Investigator: Daniel Kido


  1. Siemens Medical Systems/Radiological Society of North America

Identification of proximal coronary artery stenoses with 3D MR retrospective respiratory gating"

July 1996-June 1998, Total budget: $75,000

RSNA Fellow: Pamela Woodard

Role: Mentor: Mark Haacke


  1. MR of cerebral oxygenation in ischemia”

Principal Investigator: Colin Derdyn

Advisors: William Powers, MD and Mark Haacke, PhD

16. ^ Teaching Title and Responsibilities: Teaching in Science


During the last twenty two years, I have taught and tutored over ten courses in physics, mathematics and statistics. These courses ranged in level from freshman to senior as well as several graduate level courses and include: relativistic quantum mechanics, thermodynamics optics, statistical physics statistics, calculus general physics, and imaging physics.


In 1984, I introduced a new course at Case on the Physics of Imaging: Applications in Industry and Medicine. In 1988, this course was supplemented by a second NMR course CHM 460. In 1990/1991, this course was extended to a second semester as CHM 460. An off shoot of this course on the Mathematics of Imaging is currently being offered in the Dept. of Mathematics as MAT 457. Recent courses given at Case include (PHY 431) and optics (PHY 425). Guest lectures have been given for the last several years for two EBME undergraduate courses including EBME 105. This MRI course has been offered at Washington University through the Electrical Engineering Department from 1993 to 1999 and at Wayne State University from 2002 to present (offered in the Winter semester every other year).


Medical School and Radiology-Related Teaching


  • Coordinator, MR Physics Conferences, Dept. of Radiology 1986-1993.




  • Radiology MR Research conference: Weekly seminars on MR imaging methods and annual MRI course each fall.




  • Numerous education lectures to residents and faculty at Mallinckrodt Institute of Radiology from 1994-1999.




  • Numerous education lectures to residents and faculty at Wayne State University from 2002 to present.


17. External Examiner


The University of Western Australia. Ph.D. Thesis entitled “Non-invasive measurement and imaging of liver iron concentrations using proton magnetic resonance” by Mr. Paul Clark. June 2005.




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